ALPHA-GPC
Increase Explosive Force —
Instantly!
Driving a bench press PR into
lockout... powering a bone-crushing squat out of the hole...
smashing through sticking points like they don't exist...
Those experiences occur, but never
often enough. And, although very gratifying, improvements
in training never seem to come fast enough. We want gains
and we want them now — and we want something more every
time we go into the gym!
You may not ever be totally satisfied
with the rate of your progress, but you'd be a whole lot
happier if you mastered a key component to weight-training
success — explosive force!
Potentiate high-threshold motor units
(fast-twitch fibers) within a muscle and — BOOM! —
you've got explosive force. Activation of high-threshold
motor units is the most-important factor in maximizing muscle
growth and strength. Every advanced strength and power athlete
centers his training and competition around it.
The good news is, now there's a way
to activate these sometimes-lazy fast-twitch fibers that's
a whole lot easier and a bunch more predictable.
Do this one little thing, about an
hour before training, and get an automatic 14% increase
in peak force during training!
Not only that, you double growth hormone
(GH) levels at the time you need it most, post training.
The whole point is, the entire training
process is greatly enhanced — you'll make faster and
greater gains in muscle, strength, and overall improvements
in body composition!
The "thing" we're talking
about is a compound called alpha-GPC (alpha-glycerylphosphorylcholine).
And TMUSCLE's chief scientist, Dr. Tim Ziegenfuss, actually
proved these findings in a study that'll be published within
the year.
Not only that, Tim Patterson and Dr.
Z have been experimenting with alpha-GPC on several of TMUSCLE's
elite-level bodybuilders.
One of these bodybuilders is our very
own Christian Thibaudeau, who smashed an overhead press
PR by a whopping 30 pounds! And he did this on his very
first dose!
(We'll reveal more about this group,
as well as their training, in the months ahead.)
It's also important to note that these
effects do not diminish over time. In other words, your
100th dose works as well (maybe even better) as your first
dose.
Alpha-GPC is a precursor to the neurotransmitter
acetylcholine. Clinically, it's been used both orally and
intramuscularly to treat Alzheimer's disease, vascular dementia,
stroke, transient ischemic attack (TIA), as well as to improve
memory, cognitive function, and learning.
Clearly, you don't have to be a physician
to see that it has profound effects on the nervous system.
However, prior to Dr. Ziegenfuss, not many researchers thought
to test alpha-GPC on advanced athletes.
On the other hand, choline, which
is a precursor to alpha-GPC, has been tested on athletes
and shown to improve athletic performance and endurance.
The thinking is this:
Acetylcholine is a major neurotransmitter
that activates muscle contraction. Increasing the amount
of acetylcholine (which is depleted by exercise) in cells
can therefore keep muscles contracting longer and harder.
Simple really.
However, alpha-GPC is a much better
precursor to acetylcholine and, unlike choline, alpha-GPC
raises GH levels substantially.
That's what made this compound so
intriguing to the TMUSCLE research department, including
Dr. Tim Ziegenfuss, who decided to test it on strength athletes.
Dr. Ziegenfuss recruited experienced
weight trainers and set out to test the effects of alpha-GPC
on GH levels and explosive force, using a randomized, placebo-controlled,
cross-over design.
We can't get into the precise protocol
before the study is officially published, but we can tell
you the highlights.
Subjects consumed a dose of alpha-GPC
90 minutes prior to exercise.
They were then asked to perform 3
sets of bench-press throws using 50% of their pre-determined
1RM.
Rep speed was measured using the Ballistic
Measurement System (BMS).
Blood draws were taken 0, 5, 15, 30,
60, 90, and 120 minutes post-exercise.
Alpha-GPC increased peak force by
14% over and above the placebo value.
Alpha-GPC doubled GH levels over the
placebo value, post training.
Bottom line, alpha-GPC works. What
isn't exactly clear is how it works, but Dr. Z has narrowed
it down to two theories:
By increasing acetylcholine concentrations,
Alpha-GPC increases the number of cross bridges formed by
actin and myosin — more cross bridges equals more peak
force.
ALPHA-GPC directly increases the recruitment
of high-threshold motor units (fast-twitch fibers).
Either way, it really doesn't matter.
Alpha-GPC quickly makes athletes more powerful and much
more resistant to fatigue.
And being able to recruit more fast-twitch
fibers, repeatedly, set after set after set, you'll build
muscle and gain strength at a faster rate.
But let's not forget about the other
powerful effect of alpha-GPC, which might lead to even greater
muscle growth. I'm talking about doubling GH, of course.
Such a profound increase in GH levels
— every time you train — can have a significant
effect on fat loss, not to mention hypertrophy.
Take 900 mg to 1,200 mg, 60 —
90 minutes prior to training or competition.
BIOTEST® Fast-Acting Liquid Alpha-GPC contains the most potent, highest quality, and most pure form of L-alpha-glycerylphosphorylcholine available.
References
1. Ziegenfuss, T.N., Landis, J., J.E. Hofheins.
Acute Supplementation With Alpha-Glycerylphosphorylcholine
Augments Growth Hormone Response T, and Peak Force Production
During, Resistance Exercise. The Center for Applied Health
Science Research, Division of Sports Nutrition and Exercise
Science, Fairlawn, OH. 44333. (Abstract)
2. Abbati C, et al. Nootropic therapy of
cerebral aging. Advances in Therapy. 1991;8(6):268-276.
3. Canal N, Franceschi M, Alberoni M, et
al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia
caused by scopolamine. Int J Clin Pharmacol Ther Toxicol.
Mar1991;29(3):103.
4. Sandage, et al. Effects of Choline on
Athletic Performance and Fatigue. "The Role of Dietary
Supplements for Physically Active People,: NIH Workshop,
Bethesda, MD., 1996.
5. Spector, SA, et al. Effect of Choline
Supplementation on fatigue in trained cyclists. Med Sci
Sports Exerc 1995;27(5):669-673.
6. Conlay, AL, Sabounjian, LA and Wurtman,
R "Exercise and neuromodulators: Choline and acetylcholine
in marathon runners" International Journal of Sports
Medicine (1992) 13: S141-S142
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