|
Let's assume for a moment that
you're all-powerful; not all-powerful like, say, Donald
Trump or Oprah, but better in that you're able to manipulate
time, space, and even cellular machinery.
As an all-powerful person, you'd want
to look the part, so you'd do the alakazam, presto-chango
bit and probably do 2 or 3 things to your cellular machinery
that would allow your body to grow super big and super lean.
First, you'd probably alter muscle-fiber
properties so that your slow-twitch fibers (the "endurance"
fibers that you find in high concentrations in marathon
runners) became more like fast-twitch fibers (the kind you
find in high concentrations in sprinters, powerlifters,
and accomplished bodybuilders).
That way, the basic architecture of
your muscles would allow for "bigness."
Secondly, you'd want to alter the
sensitivity of your insulin receptors, making them as sensitive
as possible to the effects of what some people call "the
most anabolic hormone of all," insulin.
Manipulating insulin to your advantage
would have a huge nutrient-partitioning effect, driving
food (and stored food energy) into building muscle instead
of building fat.
Thirdly, you'd want to increase the
number of androgen receptors in muscle. Adding more androgen
receptors would give more sites for Testosterone to bind
to, which would mean increased muscle growth independent
of changes in your natural levels of Testosterone.
Being able to do those three things
would be terrific, wouldn't it?
Well, consider yourself all-powerful because now you can
do all three of those things with Receptormax,™ BIOTEST's
latest and greatest ground-breaking supplement.
Increases the sensitivity of insulin
receptors;
Increases the number of androgen receptors;
and even
Makes slow twitch, growth-resistant
muscle fibers act more like fast twitch, growth-anxious
muscle fibers.
By combining 5 heavily researched,
naturally occurring compounds that, in addition to building
muscle and dumping body fat, have a long list of secondary
healthful benefits (most of which will be the subject of
another article).
Acetyl-L-carnitine
Cinnamomum
burmanni (water extract, standardized for type-A polymers,
tetramers, and trimers)
Na (sodium) R-alpha-lipoic
acid
Coenzyme Q10
4-hydroxyisoleucine
Let's take a look at the research
behind these individual ingredients and examine how they
can create a lean and very muscular body.
Renowned muscle researcher Dr. Bill
Kraemer has published a handful of excellent studies showing
that the acetylated form of L-Carnitine increases androgen
receptor content following whole-body resistance training
workouts.(1)
Kraemer showed that 21 days of supplementation
with acetyl-L-carnitine led to a significant increase in
the androgen-receptor content of the vastus lateralis muscle
in the thigh. (The vastus lateralis is the traditional spot
from which to take muscle biopsies and if the number of
androgen receptors increased there, they increased in all
muscles.)
Additionally, Kraemer noted
that the athletes' blood levels of Testosterone plummeted
after a workout. While that initially sounds like a bad
thing, it's not. Instead, it shows that something good happened.
Since the "roads" (blood
vessels) had less Testosterone flowing through them, it
meant that Testosterone had pulled off the road and "parked"
in the new Testosterone receptors found on the acetyl-L-carnitine
user's muscle.
Since there were more parking spots
for Testosterone to park, it leads to more protein synthesis,
which literally means more muscle.
Furthermore, the temporarily low level
of free Testosterone in the blood stream tells the brain
(the pituitary-gonadal axis), through negative feedback,
that it needs to start producing even more Testosterone.
Another acetyl-L-carnitine
study by Volek and Kraemer showed that athletes who used
the compound after a squat workout had increased recovery.
This is due probably not only to the effects mentioned in
the previous study, but due to fewer markers of inflammation
via an increase in blood flow, oxygen delivery, and regeneration
of ATP, the energy substrate of the cell.(2)
Clearly, the discovery that acetyl-L-carnitine
increases the androgen-receptor content of muscle is a huge
deal.
But what about the other all-powerful
receptor site? What about insulin receptors?
In a study of 49 herbs, spices, and
medicinal plants known to affect insulin, good ol' common
cinnamon was shown to have the most insulin activity.(3)
Before I go on, you have to understand
that we didn't just steal momma's cinnamon from her spice
rack. Instead, we used a high grade, water-soluble extract,
standardized for the active fractions of the spice. Sure
there are other, less-expensive forms of cinnamon available,
but they aren't standardized for the active fractions. And
if a cinnamon extract contain the fat-soluble portion of
cinnamon, it may actually become toxic over time.
So what effect does Cinnamomum burmanni
have in the body?
Numerous studies have shown it to
improve the metabolic action of insulin resistance by increasing
glucose uptake by the cells and enhancing the insulin-signaling
pathway in muscle.(4)
In one study, it reduced the fasting
plasma glucose levels of patients with full-blown Type 2
diabetes by 10.3%.(5)
Another study of 60 women with Type
2 Diabetes showed a decrease of fasting glucose levels of
29%, which is an incredible increase in insulin sensitivity
and all the more impressive because the patients were diabetic.(6)
A third study showed that cinnamon
extract given to 21 adults with pre-diabetes led to a 1.1%
increase in muscle mass and a 0.7% decrease in body fat,
without exercise.(7)
Clearly, Cinnamomum burmanni extract
improves insulin sensitivity, but why is that important?
Well, for muscleheads, insulin is
a hormone that must be manipulated, regardless of your body
type. For those trying to gain muscle mass, insulin sensitivity
must be high and spiking insulin can provide a tremendous
amount of anti-catabolic effects. This can lead to large
increases in muscle mass, and this is one of the reasons
why kamikaze pro bodybuilders sometimes inject insulin.
Secondly, if you're insulin resistant
(your "parking spots" won't accept insulin), you
can end up storing a tremendous amount of body fat. At the
very least, you'd find it really difficult to get lean and
impossible to get shredded.
Lastly, not only can insulin affect
this golden pair of physique goals (muscle gain and fat
loss), but it can also affect just about every other hormone
in the body, including Testosterone.
It should be clear that having cellular
receptors that are extremely sensitive to insulin is extremely
important, and the more you can do to improve this sensitivity,
through numerous mechanisms, the better.
4-Hydroxyisoleucine is an amino acid
derived from fenugreek seeds. It activates both insulin
signaling and insulin secretion. As such, it's useful in
enhancing uptake of anabolic nutrients (including other
Receptormax™ ingredients like CoQ10 and acetyl-L-carnitine),
along with possibly regenerating muscle glycogen.(8)
A noteworthy aspect of 4-hydroxyisoleucine
is that its effects are glucose dependent. As glucose increases,
so does the insulin-promoting response elicited by 4-hydroxyisoleucine.
That means that the supplement regulates
the insulin needs of the body at any given time.
As such, medical researchers are hugely
interested in this compound and its effects on the two essential
dysfunctions of Type 2 diabetes. Accordingly, 4-hydroxyisoleucine
is regarded as the potential leader of a new class of anti-diabetic
agents.(9)
While you're presumably not diabetic,
this is simply further evidence that 4-hydroxyisoleucine
allows the physique athlete to manipulate insulin to his
advantage.
While many nutritionists regard alpha-lipoic
acid as a vitamin, it's actually a coenzyme.
It's generally regarded as one of
the most-potent antioxidants, not only because of its impressive
redox potential, but also because it's soluble in both fat
and water. This allows it to do its good work in all parts
of the body.
But that's not why we included a type
of alpha-lipoic acid in the Receptormax™ formula. In
addition to all of these healthful benefits, alpha-lipoic
acid helps increase glucose uptake in insulin-resistant
cells.(10, 11, 12)
(Remember, the more you're able to
control insulin, the better you're able to shape your body
to your specifications.)
Na R-alpha-lipoic acid (Na R-ALA)
also has a nice synergy with two other ingredients found
in Receptormax.™ In conjunction with acetyl-L-carnitine,
Na R-ALA reverses mitochondrial decay and actually restores
mitochondrial function to youthful levels.(13) (Mitochondria
are the tiny cellular organelles that produce ATP, which
is the "currency" of metabolism.)
Na R-ALA also amplifies the effects
of another one of the ingredients in Receptormax,™
Coenzyme Q10, making for a very, very, nice synergy.
While generic alpha-lipoic acid is
an impressive supplement all on its own, Receptormax™
uses Na R-alpha-lipoic acid, which is quite rightly regarded
as the "next generation" lipoic acid. Maximum
plasma levels of Na R-ALA are 30 times higher than pure
R-alpha-Lipoic acid.(14)
CoQ10 is a vitamin like, fat-soluble
compound that's found in all cells of the body. It's intimately
involved in the formation of ATP, acts as an essential antioxidant,
influences the stability, fluidity, and permeability of
cell membranes, and has beneficial effects on cell signaling
and gene expression.
However, none of that has much to
do with why CoQ10 is included in Receptormax.™
CoQ10 is unique, almost magical, in
that 300 mg per day actually alters fiber properties so
that slow-twitch muscle fibers (the ones most resistant
to hypertrophy) actually become more like fast-twitch muscle
fibers (the ones that hypertrophy easily).(15)
Additionally, 2 to 3 studies have
shown that CoQ10 improved aerobic power, anaerobic threshold,
and time to exhaustion.
Receptormax is one of those easy-to-use
supplements that doesn't require cycling. In addition to
making the body more sensitive to insulin, increasing the
androgen receptor content of muscles, and making slow twitch,
growth-resistant muscle fibers act like fast twitch, fast-growing
muscle fibers, it also has a ton of healthful benefits.
Anyone, man or woman, interested in
building their body, losing fat, or just being healthier,
should use Receptormax.™
Just take 6 capsules a day.
Non-Training
Days: Take 2 capsules a half-hour before each
of 3 meals (ideally, evenly space meals).
EXAMPLE: Take 2 capsules a half-hour before
breakfast, 2 capsules a half-hour before dinner, and 2 capsules
a half-hour before your bedtime snack.
Training Days:
Take 3 capsules a half-hour before you train, and 1 capsule
a half-hour before each of 3 meals.
EXAMPLE: Take 1 capsule a half-hour before
breakfast, 1 capsule a half-hour before lunch, 3 capsules
a half-hour before your workout, and 1 capsule a half-hour
before your bedtime snack.
Ever since the first batch of Receptormax™
arrived in the warehouse (about two weeks ago), I've been
anxiously telling all my friends and family members about
it. I want them all to be on Receptormax™ immediately!
That's how much I believe in this formula.
If you control insulin, if you can
maximize Testosterone receptor content, if you can actually
make slow twitch, growth-resistant muscle fibers act more
like fast twitch, fast-growing muscle fibers, then you practically
are all-powerful.
|
